Danni Williams hit six straight free throws near the end of overtime to send the Tennessee Lady Vols from the unbeaten ranks on Thursday night at College Station, Tex.
#6 UT had started the season 15-0, but faced four straight Top 20 teams.
The #17 Aggies won 79-76 after Tennessee started off the OT period with for straight free throws for a 74-70 advantage.
Both teams went cold near the end of the contest and wound up tied 70-70 in regulation.
Tennessee had a chance for a late shot in OT for a tie, but threw it out of bounds.
Mercedes Russell recorded 21 points and 10 rebounds to lead the Lady Vols (15-1, 3-1 SEC). The loss marks the first time Tennessee has dropped a game since being eliminated from last year's NCAA tournament on March 20.
Khaalia Hillsman led the Aggies (14-4, 3-1 SEC) with 22 points on 8-of-9 shooting from the floor and added 11 boards. Williams chipped in 22 of her own while going 3-for-7 from 3-point range. Texas A&M has now won its past two match-ups with the Lady Vols and the last two meetings in College Station, both in overtime.
Jaime Nared added 18 points for the Lady Vols, including four 3-pointers. Rennia Davis and Cheridene Green netted 12 each, and Evina Westbrookput up nine points while dishing out seven assists.